abstract：:We describe four patients who developed basal cell carcinoma (BCC) among multiple facial trichoepitheliomas. The only clinical feature that distinguished the carcinomas from the trichoepitheliomas was their larger size in three of the four patients. None of the lesions ulcerated. Whether the BCCs developed independent...

journal_title：Journal of the American Academy of Dermatology

authors： Johnson SC,Bennett RG

更新日期：1993-02-01 00:00:00

abstract：:We describe a 2 1/2-year-old boy who has hirsutism and ringed creases of the extremities associated with an underlying smooth muscle hamartoma. Cutaneous findings in this child resemble those in other reports of the "Michelin tire syndrome." Histologic examination showed numerous well-demarcated fascicles of smooth mu...

journal_title：Journal of the American Academy of Dermatology

authors： Schnur RE,Herzberg AJ,Spinner N,Kant JA,Magnusson M,McDonald-McGinn D,Rehberg K,Honig PJ,Zackai EH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Renal allograft transplantation is associated with an increased incidence of malignant melanoma. The development of excess melanocytic nevi may be an indicator of this risk. OBJECTIVE:This study determines the prevalence of melanocytic nevi in children who have received renal allografts. METHODS:Total and ...

journal_title：Journal of the American Academy of Dermatology

authors： Smith CH,McGregor JM,Barker JN,Morris RW,Rigden SP,MacDonald DM

更新日期：1993-01-01 00:00:00

abstract：:A patient who had pemphigus vulgaris received therapy with gold thiomalate in addition to dexamethasone. Three weeks after the initiation of parenteral gold the patient developed acute hepatitis. Causes other than gold toxicity were ruled out, and the patient recovered completely after discontinuation of gold therapy....

journal_title：Journal of the American Academy of Dermatology

authors： Rye B,Krusinski PA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:There has been considerable controversy about the relation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE). OBJECTIVE:We describe the clinical and histopathologic differences between the two diseases. METHODS:We reviewed clinical findings and histopathologic changes in two c...

journal_title：Journal of the American Academy of Dermatology

authors： Chun SI,Ji HG

更新日期：1992-12-01 00:00:00

abstract：:Isotretinoin is most effective for patients with acne who fail to respond to other forms of treatment; virtually all patients respond to isotretinoin, 0.5 to 1.0 mg/kg/day. As many as 61% of patients are cured after one course, but 39% require further isotretinoin (16%) or oral antibiotics (23%). The relapse rate can ...

journal_title：Journal of the American Academy of Dermatology

authors： Layton AM,Cunliffe WJ

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Pigmented Spitz nevi have distinct clinical features but often may be difficult to differentiate from malignant melanoma by clinical criteria. OBJECTIVE:The purpose of this study was to use a new noninvasive diagnostic approach to improve the clinical diagnosis of Spitz nevi. METHODS:Epiluminescence micros...

journal_title：Journal of the American Academy of Dermatology

authors： Steiner A,Pehamberger H,Binder M,Wolff K

更新日期：1992-11-01 00:00:00

abstract：:This is the second reported case of minocycline-induced Sweet's syndrome (and the first such case to appear in the American literature). The syndrome developed in a 32-year-old man 10 days after minocycline therapy for acne was begun and resolved rapidly after discontinuation of the medication and start of oral predni...

journal_title：Journal of the American Academy of Dermatology

authors： Thibault MJ,Billick RC,Srolovitz H

更新日期：1992-11-01 00:00:00

abstract：:We describe a patient with chronic actinic dermatitis whose photopatch tests revealed reactions to musk ketone and musk ambrette, both of which were found in his aftershave lotion. Minimal erythema doses of UVA and UVB were decreased. After initial unsuccessful treatment with PUVA therapy the patient was successfully ...

journal_title：Journal of the American Academy of Dermatology

authors： Gardeazábal J,Arregui MA,Gil N,Landa N,Ratón JA,Diáz-Pérez JL

更新日期：1992-11-01 00:00:00

abstract：:Three patients who had cardiac surgery developed a transient, noninflammatory subepidermal bullous eruption on the legs after epsilon-aminocaproic acid infusion. Fibrin thrombi were demonstrated in papillary dermal vessels. The use of epsilon-aminocaproic acid as an antifibrinolytic agent may predispose patients to cu...

journal_title：Journal of the American Academy of Dermatology

authors： Brooke CP,Spiers EM,Omura EF

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:The focal facial dermal dysplasias (FFDD) are a genetically heterogeneous group of disorders characterized by congenital bilateral scarlike facial lesions, with or without associated facial anomalies. The cases have been reported under various names; thus the nosology is confusing and unclear. OBJECTIVE:Our...

journal_title：Journal of the American Academy of Dermatology

authors： Kowalski DC,Fenske NA

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Molluscum contagiosum (MC) is a common and at times severely disfiguring cutaneous viral infection in patients with human immunodeficiency virus (HIV) infection. OBJECTIVE:The purpose of this study was to describe the clinical course of MC in patients with HIV infection and to examine the relation between p...

journal_title：Journal of the American Academy of Dermatology

authors： Schwartz JJ,Myskowski PL

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia has received little attention as a side effect of cyclosporine therapy for severe psoriasis. OBJECTIVE:We report changes in fasting serum lipids in patients treated with low-dose oral cyclosporine for psoriasis and discuss their significance. METHODS:Twenty-two patients with severe, recalcit...

journal_title：Journal of the American Academy of Dermatology

authors： Stiller MJ,Pak GH,Kenny C,Jondreau L,Davis I,Wachsman S,Shupack JL

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:This study was undertaken to evaluate the effectiveness and safety of the 577 nm pulsed dye laser in the treatment of various vascular lesions of the face. OBJECTIVE:Our purpose was to make observations on the effects of different variables that could affect response. METHODS:Ninety-two adults with telangi...

journal_title：Journal of the American Academy of Dermatology

authors： Gonzalez E,Gange RW,Momtaz KT

更新日期：1992-08-01 00:00:00

abstract：:Lipoid proteinosis (Urbach-Wiethe disease) is a rare, recessively inherited disorder that is characterized by the deposition of hyaline-like material in the skin, oral cavity, and other tissues. It usually appears in infancy with hoarseness. We report a case of lipoid proteinosis in a 10-year-old boy that demonstrates...

journal_title：Journal of the American Academy of Dermatology

authors： Konstantinov K,Kabakchiev P,Karchev T,Kobayasi T,Ullman S

更新日期：1992-08-01 00:00:00

abstract：:The first reported case of phenytoin-induced generalized nodular cutaneous pseudolymphoma without symptoms of the phenytoin hypersensitivity syndrome is presented. Despite the malignant histologic appearance of the dermal infiltrate, T-cell receptor gene rearrangement studies did not demonstrate monoclonality. The cut...

journal_title：Journal of the American Academy of Dermatology

authors： Braddock SW,Harrington D,Vose J

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Because of the relatively rare occurrence of malignant melanoma (MM) of the eyelid, prognostic factors in relation to survival in these patients have not been established. OBJECTIVE:Our purpose was to examine prognostic indicators in relation to survival in patients with MM of the eyelid. METHODS:All patie...

journal_title：Journal of the American Academy of Dermatology

authors： Tahery DP,Goldberg R,Moy RL

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Often after biopsy a skin cancer appears to resolve clinically and a repeat biopsy may be done on the area in question before proceeding with further treatment. OBJECTIVE:Our purpose was to assess the value of a subsequent biopsy in the treatment of skin cancers previously diagnosed by biopsy results. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Torres A,Seeburger J,Robison D,Glogau R

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The eruptive appearance of numerous seborrheic keratoses, the sign of Leser-Trélat, has been regarded as a reliable cutaneous marker of internal malignancy. OBJECTIVE:We have evaluated the possible association of malignant disease and the sign in 1752 consecutive cases of seborrheic keratoses. METHODS:Firs...

journal_title：Journal of the American Academy of Dermatology

authors： Lindelöf B,Sigurgeirsson B,Melander S

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Despite the prevalence of androgenetic alopecia among men, little is known about its psychological effects. OBJECTIVE:This investigation examined the psychosocial sequelae that balding men attribute to hair loss and compared balding and nonbalding men in personality functioning. METHODS:Subjects included 6...

journal_title：Journal of the American Academy of Dermatology

authors： Cash TF

更新日期：1992-06-01 00:00:00

abstract：:A case of porphyria cutanea tarda in a human immunodeficiency virus-infected patient with hemophilia is reported. Onset of skin manifestations of porphyria cutanea tarda coincided with deterioration of immune function. However, acquired immunodeficiency syndrome has not yet developed with a follow-up interval of 39 mo...

journal_title：Journal of the American Academy of Dermatology

authors： Conlan MG,Hoots WK

更新日期：1992-05-01 00:00:00

abstract：:Cutaneous T-cell lymphoma is a malignancy of T cells that express a clone-specific heterodimer T-cell receptor for antigen. The second recognized case of an epidermotropic malignancy of T-cells expressing gamma/delta T-cell receptor-expressing cells is reported. The immunophenotype of the malignant T-cells was CD3+, C...

journal_title：Journal of the American Academy of Dermatology

authors： Heald P,Buckley P,Gilliam A,Perez M,Knobler R,Kacinski B,Edelson R

更新日期：1992-05-01 00:00:00

abstract：:Angiolymphoid hyperplasia with eosinophilia developed in a 13-year-old boy. The immune phenotype of infiltrating cells and the distribution of adhesion molecules of the integrin, immunoglobulin, and selectin families were analyzed with monoclonal antibodies. The infiltrate consisted mainly of helper lymphocytes, monoc...

journal_title：Journal of the American Academy of Dermatology

authors： von den Driesch P,Gruschwitz M,Schell H,Sterry W

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:HLA-DR1 is associated with the development of multiple basal cell carcinomas (BCC). However, the association is weak. OBJECTIVE:The purpose of our study was to determine whether HLA-DR1 is a marker for susceptibility to the development of many BCCs during a lifetime. METHODS:Persons with multiple BCCs were...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B,Nash C

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Relatively few persons with obsessive-compulsive disorder (OCD) come to psychiatric clinics for treatment. Our hypothesis was that patients with a form of OCD that involves compulsive hand and body washing might initially seek treatment from a dermatologist. OBJECTIVE:Our purpose was to screen patients atte...

journal_title：Journal of the American Academy of Dermatology

authors： Hatch ML,Paradis C,Friedman S,Popkin M,Shalita AR

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Women with stage I malignant melanoma (MM) have a survival advantage over men as judged by univariate analysis. However, on multivariate analysis, gender was found to be an independent predictor of survival in only 8 of 14 published studies. OBJECTIVE:This study attempts to explain the disparate findings fo...

journal_title：Journal of the American Academy of Dermatology

authors： Vossaert KA,Silverman MK,Kopf AW,Bart RS,Rigel DS,Friedman RJ,Levenstein M

更新日期：1992-03-01 00:00:00

abstract：:A 46-year-old white man had classic findings of scleredema; subsequently, a monoclonal immunoglobulin G lambda light chain was detected in his serum. Findings of a bone marrow biopsy specimen revealed that he had an increased percentage of plasma cells, some of which were atypical. A diagnosis of scleredema and smolde...

journal_title：Journal of the American Academy of Dermatology

authors： Schmidt KT,Gattuso P,Messmore H,Shrit MA,Massa M,Welykyj S

更新日期：1992-02-01 00:00:00

abstract：:We report a case of drug-induced pemphigus caused by an angiotensin-converting enzyme inhibitor, captopril. The cutaneous reaction remitted after withdrawal of captopril therapy. Unique to this case, however, was the substitution of another angiotensin-converting enzyme inhibitor, enalapril, without exacerbation of th...

journal_title：Journal of the American Academy of Dermatology

authors： Kaplan RP,Potter TS,Fox JN

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Since the late 1970s clinical criteria for dysplastic melanocytic nevi (DMN) have been proposed and discussed. However, to our knowledge, no rigorous quantitative evaluation of the ability of examiners to agree on the gross morphologic features ascribed to DMN or atypical melanocytic lesions in general has b...

journal_title：Journal of the American Academy of Dermatology

authors： Barnhill RL,Roush GC,Ernstoff MS,Kirkwood JM

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Despite a high incidence of xeroderma pigmentosum, there is no previous publication from Libya. OBJECTIVE:The purpose was to study the clinical profile of Libyan cases of xeroderma pigmentosum. METHODS:With the help of a special protocol, 24 cases of xeroderma pigmentosum treated between 1981 and 1990 were...

journal_title：Journal of the American Academy of Dermatology

authors： Khatri ML,Shafi M,Mashina A

更新日期：1992-01-01 00:00:00

abstract：:Discoid lupus erythematosus lesions show hyperkeratosis and atrophy, which may reflect abnormal epidermal proliferation, differentiation, or both. In this investigation, markers for epidermal proliferation, differentiation and inflammation were studied in cutaneous lesions of discoid lupus erythematosus. Frozen sectio...

journal_title：Journal of the American Academy of Dermatology

authors： de Jong EM,van Erp PE,Ruiter DJ,van de Kerkhof PC

更新日期：1991-12-01 00:00:00

abstract：:Multiple modalities exist for the treatment of keratoacanthoma. Excisional surgery is currently the treatment of choice for the majority of keratoacanthomas. This can result in functional and cosmetic defects when large or strategically located lesions are treated. An effective nonsurgical treatment would be desirable...

journal_title：Journal of the American Academy of Dermatology

authors： Melton JL,Nelson BR,Stough DB,Brown MD,Swanson NA,Johnson TM

更新日期：1991-12-01 00:00:00

abstract：:In two double-blind, parallel-group, multicenter trials, 0.05% halobetasol propionate cream was compared with 0.05% clobetasol 17-propionate cream and 0.05% betamethasone dipropionate cream in 264 patients with acute, severe exacerbations of atopic dermatitis. The efficacy of halobetasol propionate cream and betametha...

journal_title：Journal of the American Academy of Dermatology

authors： Yawalkar SJ,Schwerzmann L

更新日期：1991-12-01 00:00:00

abstract：:A cutaneous and soft tissue reaction that resulted from a broken thermometer inside the mouth of a 10-year-old boy is described. Metallic mercury globules and glass pieces were identified in the excised tissue. On histologic examination, a zone of necrosis, polymorphonuclear leukocytes, macrophages, and multinucleated...

journal_title：Journal of the American Academy of Dermatology

authors： Sau P,Solivan G,Johnson FB

更新日期：1991-11-01 00:00:00

abstract：:In this article we describe the immunocytochemical and electron microscopic findings in five patients with toxic epidermal necrolysis. They indicate the occurrence of necrotic keratinocytes with nuclear disintegration associated with apposed dendritic cells with the nuclear chromatin configuration of T lymphocytes. Th...

journal_title：Journal of the American Academy of Dermatology

authors： Heng MC,Allen SG

更新日期：1991-11-01 00:00:00

abstract：:The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Skelton HG 3rd,Giblin WL,James WD

更新日期：1991-11-01 00:00:00

abstract：:Four cases of Laugier-Hunziker syndrome are described. In all patients (two men and two women between 39 and 57 years of age) pigmentation of the lower lip and hard palate was found. in addition, two patients had involvement of the buccal mucosa; another patient also had pigmentation of the upper lip, the gums, the so...

journal_title：Journal of the American Academy of Dermatology

authors： Veraldi S,Cavicchini S,Benelli C,Gasparini G

更新日期：1991-10-01 00:00:00

abstract：:In a randomized, double-blind comparative study 60 patients with severe, widespread psoriasis were treated either with photochemotherapy (PUVA) alone or in combination with acitretin. Forty-eight patients completed the study; of these, 25 received placebo combined with PUVA and 23 received acitretin with PUVA. Marked ...

journal_title：Journal of the American Academy of Dermatology

authors： Tanew A,Guggenbichler A,Hönigsmann H,Geiger JM,Fritsch P

更新日期：1991-10-01 00:00:00

abstract：:A newly recognized and well-described connective tissue disease, eosinophilia-myalgia syndrome, is thought to relate to L-tryptophan ingestion. The suspect L-tryptophan made in Japan has been distributed in Japan and in the United States. Different from many case reports of eosinophilia-myalgia syndrome in the United ...

journal_title：Journal of the American Academy of Dermatology

authors： Mizutani T,Mizutani H,Hashimoto K,Nakamura Y,Kishida M,Taniguchi H,Murata M,Kuzuhara S,Shimizu M

更新日期：1991-09-01 00:00:00

abstract：:Cutaneous multilobated T-cell lymphoma is an uncommon variant of skin-based peripheral T-cell lymphoma typically characterized by cutaneous nodules in elderly patients and a chronic clinical course. We report a case of the disease that led to the patient's death within 2 years after onset. This disease may be associat...

journal_title：Journal of the American Academy of Dermatology

authors： Goldman BD,Bari M,Kantor GR,Kadin ME,Micaily B,Vonderheid EC

更新日期：1991-08-01 00:00:00